Current-status and applications of polysaccharides in drug delivery systems
نویسندگان
چکیده
The polysaccharide-based advanced drug delivery system owing to their biocompatibility, ability encapsulate the molecules in interspaces, and achieve a controlled release of cargo result improved pharmacokinetics. drug-loaded polysaccharides possess evade multidrug-resistant microbial efflux pumps by aggregation effect, whereas loaded polysaccharide-fabricated metal nanoparticles present an exceptional candidature for effectively transporting across membrane barriers while enabling theranostic applications at same time. biodegradability polysaccharide based systems ensure sustained encapsulated molecules, which minimizes side effects caused burst therapeutics. These proved highly beneficial NSAIDs that otherwise manifest ulcerogenic effect gastrointestinal tract. large surface area further provide higher drug-loading capacity, maintains optimal concentration target sites. emerging biodegradable designing multicompartmental microspheres revolutionized tissue engineering, multi delivery, cell culturing technologies. review deals with current-status as systems.
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ژورنال
عنوان ژورنال: Colloid and Interface Science Communications
سال: 2021
ISSN: ['2215-0382']
DOI: https://doi.org/10.1016/j.colcom.2021.100418